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[1] Note: The principal limitation of the study is that there was no randomization, meaning that subjects chose the study arm in which they wanted to participate. Normally, non-randomization can be a problem, because study subjects who choose a diet they believe to be healthy are likely to be more motivated to adhere to it and improve their health habits in various other ways as well. Whereas: those choosing a placebo know their treatment is ineffective and are unlikely to feel motivated. However, in this trial, since all subject were choosing their own diets, presumably they all felt they made the best choice, and one could reasonably assume they all felt equally motivated to follow them. Moreover, even with some distortion from non-randomization, self-selection could not explain a 60% vs. zero result in diabetes reversal.
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